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Symbol Name ID |
Srgap1
SLIT-ROBO Rho GTPase activating protein 1 MGI:2152936 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | renal/urinary system phenotype |
increased mesangial cell number |
detached podocyte |
albuminuria |
podocyte foot process effacement |
absent podocyte slit diaphragm |
decreased podocyte number |
expanded mesangial matrix |
glomerulosclerosis |
dilated renal tubule |
renal cast |
abnormal glomerular filtration barrier function |
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| Availability | Mouse Genotype | ||||||||||||
| Srgap1tm1a(KOMP)Wtsi/Srgap1tm1a(KOMP)Wtsi Six2tm1(tTA,tetO-EGFP/cre)Amc/Six2+ (conditional) |
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| Srgap1tm1a(KOMP)Wtsi/Srgap1tm1a(KOMP)Wtsi Tg(NPHS2-cre)295Lbh/0 (conditional) |
* | ||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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